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Abstract
The regular consumption of foods and beverages rich in powerful antioxidant phytochemicals has been associated with reduced risks of chronic diseases. For this reason, the antioxidative and anti-glycative activities of Concord and muscadine grape juices and wines were investigated. Though the total phenolics' content of muscadine and Concord grape beverages were similar, the H-ORACFL value of muscadine products were significantly greater than those of Concord grape products. Furthermore, muscadine juice and wine retarded bovine serum albumin glycation to a greater extent than Concord juice and when incubations were performed on equi-volumetric and -phenolic bases. When applied to Caco-2 cells, muscadine products exhibited significantly greater cellular antioxidant activity than the Concord products. Interestingly, the juices of each grape displayed significantly greater anti-glycative and cellular antioxidant activity than their wines. These results indicate that consumption of muscadine products may offer greater health benefits than that of Concord products.