Daylily rust, caused by Puccinia hemerocallidis, increasingly has become a management issue for growers throughout the southeastern United States. Fungicides remain the most effective tool in managing daylily rust. Foliar sprays of azoxystrobin, propiconazole, thiophanate-methyl, and chlorothalonil were evaluated on field-grown daylilies in 2014. Only treatments containing azoxystrobin provided acceptable rust management and all other treatments were no different than untreated controls. In 2015, foliar sprays of pyraclostrobin, tebuconazole, myclobutanil, flutolanil, pyraclostrobin + boscalid, chlorothalonil, and mancozeb were evaluated. All systemic chemicals provided acceptable levels of management; however, treatments containing tebuconazole outperformed all others. In addition, tebuconazole has the lowest material cost of all the systemic chemicals in this study. Fungicide sensitivity profiles for pyraclostrobin, flutolanil, and thiophanate-methyl were evaluated and isolates were found to be most sensitive to pyraclostrobin and least sensitive to thiophanate-methyl. The broadest range of sensitivity was observed with flutolanil.