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Abstract
Bovine coronavirus (BCoV) and Bovine rotavirus (BRV) are frequently associated with neonatal calf diarrhea (NCD) in young calves, representing economic consequences in livestock. In this study, neutralizing antibody assay in serum (SNA) and colostrum (CNA) and radial immunodiffusion in serum were used to evaluate the effects of injectable trace minerals (ITM) concurrent with NCD vaccination in pregnant cattle. The results show that ITM-heifers had slightly higher geometric mean of BCoV SNA titers, without statistical differences, and higher percentage of animals undergoing seroconversion on days 21 and 35. In addition, ITM-heifers had slightly median increase of colostrum quality and higher CNA titers against BCoV than control, but without statistical significance. CNA against BRV titers in control group were higher than the titers of ITM, with no statistical difference. Calves from ITM-heifers exhibited relatively higher titers of BCoV without statistical significance. These results suggest that ITM could enhance humoral response to NCD vaccines.