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Abstract
Oxygen reduction catalysts are of great interest both as a source of renewable energy as well as serving biological relevance. One such example is Cytochrome C oxidase which is known to reduce O2 into H2O. To develop catalyst that also does this, a deep understanding of structure property relationship between Cytochrome C oxidase and O2 interaction is necessary. Such catalyst typically uses a Fe centered porphyrin, like the case of Cytochrome C oxidase. However, much work is done in looking at secondary coordination sphere effect for these catalyst diving into the mechanistic studies that these oxygen reduction catalysts go through. This work aims to summarize the current O2 reduction catalyst and current advancements in the field.