One of the costliest diseases to affect the poultry industry is coccidiosis. Eimeria parasites (coccidia) can cause poor growth performance and increased feed conversion in broilers. A series of three experiments were conducted to evaluate the effects that management practices have on the efficacy of coccidiosis control methods commonly used in commercial broilers. Experiment 1 showed that there were no advantages to using a bioshuttle program compared to either a live coccidiosis vaccine or an ionophore program when raising broilers to 49 days. In Experiment 2, the use of dietary salinomycin and a live coccidiosis vaccine showed similar results on performance parameters and that the live coccidiosis vaccine provided better protection against Eimeria maxima. The effects that environmental temperature and dietary protein concentrations have on broilers given a live coccidiosis vaccine, at day of hatch, was observed in Experiment 3. In conclusion, management practices can affect coccidiosis control methods used in broilers.