This is the endline report from a multi-year study that aimed to estimate prevalence of sex trafficking among women engaged in commercial sex (WECS) and implement supportive services for survivors of sex trafficking in Senegal’s Kédougou region, Kédougou and Saraya Departments. CenHTRO conducted a baseline study in 2021 which found that approximately 20% of WECS (aged 18–30 years) were victims of sex trafficking (Okech et al., 2022). The study identified economic hardship, lack of social support, ineffective law enforcement, and corruption in transit countries as key factors driving vulnerability to trafficking. Following the 2021 study, CenHTRO coordinated with Senegalese and Nigerian stakeholders and NGOs to provide protection, prevention and prosecution services for survivors of sex trafficking and to strengthen sex trafficking response policies within Senegal. The present study aims to assess changes in sex trafficking prevalence, perceptions, and policies since 2021. Specific objectives include measuring the current prevalence among WECS in the Kédougou and Saraya departments, comparing changes in sex trafficking prevalence since the baseline study, evaluating shifts in community perceptions and policies, and assessing the impact of the shifts in community perceptions and policies on survivors. This endline study utilized a mixed methods design, combining quantitative surveys and qualitative interviews with women in commercial sex, sex trafficking survivors, key government stakeholders, and CenHTRO program implementers.