Ecological landscape rehabilitation is explored in cities, especially the significance of scale, and the sense of place that is encouraged through the use of an indigenous vegetation model. The natural landscape and natural processes in cities have been modified beyond recognition, simplified, and obscured; however, the dependence of people on those processes and resources remains in a critical, tenuous, and not completely understood balance. In process-based ecological restoration, considerations of scale are related to ecosystem spatial characteristics and potential connectivity of restored patches. In cities, with unbuilt ground in very small fragments, the idea of a whole ecological landscape integrated with dense human population encourages consideration of larger scale rehabilitation. A process of ecological rehabilitation at a neighborhood scale is suggested, toward success in ecological and social terms, by considering case study neighborhoods in central city Milwaukee, their characteristics relevant to landscape rehabilitation, and oak savanna as a vegetation model.