HiDEW: high-speed determination of epigenetic code rendered through a Web application

Histone modifications, especially methylations, play a vital role in transcriptional activation of genes within a human body. Hence, we created a web service to help users to study the local spatial structure of these modifications along a chromosome along with their patterns. We created four queries for this purpose. A memory mapping technique along with binary search was used to help obtain quick output results of these queries. We also created a tree representation to view the homogenous regions of these modifications as we walk through the chromosome. We not only show there is a large non-uniformity of the spatial distribution of epigenetic marks in these regions, but also that there are a large number of regions which are locally multinomial.