Southern corn rust (SCR) caused by Puccinia polysora and northern corn leaf blight (NCLB) caused by Exserohilum turcicum are important foliar diseases of corn in the southern United States. Field experiments were conducted to determine the effect of hybrid, fungicide and timing of fungicide application on NCLB and SCR epidemics and corn yield. The Rpp9-virulent and Rpp9-avirulent races of P. polysora were characterized in the field. Onset of SCR in Pioneer 33M52 was delayed in early-planted trials but not in later-planted trials. Area under the disease progress curves (AUDPC) for SCR were lower and yields were higher in Pioneer 33M52 than in Pioneer 33M57 when this disease was severe. Fungicides were usually most effective when applied near disease onset. When both diseases were severe, multiple fungicide applications improved disease management and yield. In vitro sensitivity assays indicated a range of EC50 values from 0.008 to 0.155 g/ml. These results can be used to further develop management guidelines for SCR and NCLB