This study aimed to explore the effect of nisin on the growth kinetics of Bacillus cereus in LWE. Samples supplemented with 0- 6.25 ppm of nisin were inoculated with a four-strain cocktail of B. cereus spores (heat-shocked) and incubated 15-45 °C. Baranyi model was fitted to all B. cereus isothermal growth profiles to generate µmax and lag phase duration (LPD). The statistical analysis showed that, while LPD of B. cereus was affected by both storage temperature and nisin concentration, µmax was not affected by nisin concentrations. The extended Ratkowsky model and polynomial model were used as secondary model for µmax and LPD, respectively. A tertiary model was developed and validated using three dynamic temperature profiles, which showed that the model accurately predicted the growth rate but overpredicted the LPD, making it “fail-safe”. This disagreement was addressed by adjusting different h0 values for each experimental setup, which improved the model's accuracy.