Issues faced by Mexican American Immigrants in the Southwestern United States are explored through literature review. Issues uncovered are compared and contrasted with the issues uncovered in the literature on Mexican American Immigrants in the Southeast, specifically, Athens-Clarke County, Georgia. These issues are categorized into economic issues, documentation issues, poverty issues, issues regarding public sentiment, and education issues. Evidence of these issues is examined through interviews with key informants who have a working knowledge of, and with the Mexican American Immigrant community in Athens-Clarke County. Synthesis and evaluation of the similarities and differences between issues in both regions of the United States are used to present the possible implications that these issues have in the economic, social and political realms.