Although regionalism has proliferated in sub-Saharan Africa since the advent of decolonization, success in terms of economic development are not promising. Examining intra-regional trade shows that there has been an increase as a result of regional trade integration; however the rate of increase differs among 4 key blocs in sub-Saharan Africa. This paper examines and test factors that affect the level of intra-regional trade among four regional trading blocs in sub-Saharan Africa: the Common Market for Eastern and Southern Africa (COMESA), the East African Community (EAC), the Economic Community of West African States (ECOWAS), and the Southern African Development Community (SADC).