The House on Saint Julian is a gothic-horror novel set in Savannah, Georgia in 1874. In the opening chapter Saul Richardson is killed by a demon while in Saint Josephs Hospital. The death is witnessed by a nun, Sister Brigid, who was born to a family of wise women in Ireland. The church summons its magicians to deal with the demon, but the demon is too powerful. Brigid must rely on her few pagan connections remaining in Ireland to find a magician who can destroy the demon. In the course of the novel she recovers her pagan heritage and faith, led to her true path by another hereditary witch, Sister Angela, and the Voudon mambo, Esmerelda. At the conclusion of the novel, the two nuns leave the church and leave together for Sicily.