Research trends in multispecies interactions reflect the role of inequalities within the critical medical anthropology framework related to the human physical and social environments. Using this framework, this study explores the utility of using a social vulnerability index (SVI) to explain health variations within the dog intake population of an open admissions animal shelter in a Georgia community. The US Centers for Disease Control and Prevention developed SVI using domain data derived from the US Census to analyze and rank census tracts for SVI nationwide. Social vulnerability is the product of social inequalities and inequalities related to the human built environment. Results of this study indicate the utility of non-animal focused data when developing companion animal community health programs through the association between dog health characteristics, and overall SVI. The close relationship between humans and dogs reflects multispecies interactions related to the human built environment.